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      Bcl2 antibody, Bcl-2抗體

      編 號 PR-1237
      產品名稱 Bcl2 antibody, Bcl-2抗體
      規 格 0.2ml
      價 格 1980元
      品 牌 Hopebiot

      詳細信息: 說明書下載

      Background:  The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas.Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal.Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action.A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2.Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2.

      Description: Rabbit polyclonal to Bcl2

      Immunogen: KLH conjugated synthetic peptide derived from Bcl2

      Specificity:  ·Reacts with Human, Mouse, Pig, Rabbit, Cow, Dog and Rat.

      ·Isotype: IgG

      Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 26 kDa;

      ·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

      ·Immunocytochemistry: 1/100-200;

      ·ELISA: 1/500;

      ·Optimal working dilutions must be determined by the end user.


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