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          FKBP38 Antibody, FK506結合蛋白38抗體

           
          編 號 PR-1023
          產品名稱 FKBP38 Antibody, FK506結合蛋白38抗體
          規 格 0.2ml
          價 格 1980元
          應 用 IHC,WB,ELISA,ICC,IP,IF
          品 牌 Hopebiot

          詳細信息: 說明書下載

          Background:  FKBP38 (FK506-binding protein 38), a member of the immunophilin family, has been implicated to play an important role in apoptosis through its involvement in the mechanism that targets Bcl-2 and Bcl-xL to the outer mitochondrial membrane (OMM). Suppression of endogenous FKBP38 by RNAi or transfection of a mutant FKBP38 missing the transmembrane domain necessary for mitochondrial insertion, resulted in the translocation of Bcl-2 and Bcl-xL from the OMM to the cytosol. It has also been suggested that FKBP38 may play a role in the cross-talk between the Bcl-2 and the Calcineurin/NF-AT apoptosis signaling pathways and in cell size regulation through interactions with tuberous sclerosis genes.

          Description: Rabbit polyclonal to FKBP38

          Immunogen: KLH conjugated synthetic peptide derived from FKBP38

          Specificity:  ·Reacts with Human, Mouse, Dog, Cow, Chicken and Rat.

          ·Isotype: IgG

          Application:  ·Western blotting: 1/500-1000. Predicted Mol wt: 45 kDa;

          ·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

          ·Immunocytochemistry: 1/200;

          ·ELISA: 1/500;

          ·Optimal working dilutions must be determined by the end user.

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